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Taken from WWW.pubmed.gov (testosterone studies)
Int J Clin Pract. 2007 Feb;61(2):341-4.
Hypoandrogen-metabolic syndrome: a potentially common and underdiagnosed
condition in men.
· Gould DC,
· Kirby RS,
· Amoroso P.
The Prostate Centre, London, UK. duncangould@hotmail.com
Recently, it has been proposed that hypoandrogenaemia (hypogonadism, hypotestosteronaemia) may be a common
accompanying factor in men with the metabolic syndrome
(insulin resistance, Reaven's syndrome or syndrome X). When they are present together they may be considered
as a specific entity, the hypoandrogen-metabolic (HAM) syndrome. The metabolic syndrome is common and its
prevalence is predicted to increase in coming years. Hypoandrogenaemia, often unrecognised, is also common
and may be an aetiological factor in the development of the metabolic syndrome in men. The prevalence of
both hypoandrogenaemia and the metabolic syndrome increases with age and the clinician will frequently
attend to men in their middle to advanced years with obesity, low androgen levels and metabolic syndrome.
These conditions place men at an increased risk of cardiovascular and coronary heart disease and type 2
diabetes and can be simply investigated with weight, waist and blood pressure measurement and blood sample
analyses. Men with HAM and symptoms of androgen deficiency may be managed by, in the absence of
contraindications, testosterone replacement therapy along with weight reduction and other measures to
normalise glucose, lipid and blood pressure control.
PMID: 17263722 [PubMed - in process]
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